The truism about this subject matter falls within the contextual terms of “depression’ and ‘anxiety’ before proper proceedings on the subsets of the act of mindfulness, let us define the state of mindfulness and know its prerogative link with depression and anxiety . From the English advanced learner’s dictionary, it defined mindfulness as an act of being aware. However, this form of awareness can come in two forms consciously or subconsciously. With this explanatory views let us decipher the meaning of depression and anxiety. Depression in psychotherapy and psychiatry is a period of unhappiness or low morale which lasts longer than several weeks and may include ideation of self-inflicted injury or suicide while anxiety is an unpleasant state of mental uneasiness, nervousness, apprehension and obsession or concern about some uncertain event. Be that as it may, these two wonderful definitions are linked with mindfulness which has a base in the cognitive faculty, the practice of mindfulness and its salient help to depression and anxiety. A human mind is filled with activities of the past, present and future as it tries to unravel many mysteries or to fathom the reason behind his failure and success stories, that is when the mind begins to suffer from its negative or positive result. When anxiety occurs in a man as regards to achieving an important task or objective, perhaps if this objective is not achieve after a whole lot of brain work thus depression sets in.